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Arsenal has been hit with a significant setback as William Saliba is expected to be sidelined for three to four weeks, according to reports from France.
The central defender was forced to leave the pitch just minutes into Arsenal's game against Liverpool due to an ankle injury.
Saliba had to withdraw from international duty with the French national team after limping off the field.
The 24-year-old could now miss up to a month of action as Arsenal looks to bounce back and prepare for the start of the Champions League following the international break.
Earlier this week, the French national team released a statement saying: "William Saliba, who started for Arsenal against Liverpool on Sunday, was forced off in the fifth minute.
After a discussion with Franck Le Gall, the French team doctor, Didier Deschamps confirmed the unavailability of William Saliba.
If his recovery takes longer than expected, he could also miss fixtures against Newcastle, Olympiacos and West Ham United.
Summer recruit Cristhian Mosquera, 21, stepped in to replace Saliba during the Liverpool game.
William Saliba could miss a month of action for Arsenal