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Liverpool has released a statement confirming the news, and so has the Portuguese Football Federation.
Jota's brother, Andre Silva, also died in the car crash.
He played for Penafiel, a club in the second tier of Portuguese soccer.
Liverpool's statement read: "Liverpool Football Club are devastated by the tragic passing of Diogo Jota.
Our heartfelt condolences are with Diogo’s young family, friends, and everyone at Liverpool Football Club during this incredibly difficult time
Our thoughts and condolences are with his family, friends and all at Liverpool Football Club at this incredibly difficult time."
Manchester United wrote: "Our deepest condolences are with the loved ones of Diogo Jota and his brother, Andre, and everyone connected with Liverpool FC following today’s heartbreaking news."
Jamie Carragher is among the Liverpool legends to pay tribute
He wrote on X: "Devastating news about Diogo Jota and his brother Andre this morning
Thoughts are with everyone of their family & friends, especially his wife Rute and their three lovely kids."
Gary Neville, meanwhile, wrote on X: "That is heartbreaking news on Diogo Jota and his brother
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