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Arne Slot has even had to defend his decision to sign both the Swede and Hugo Ekitike, with the Reds now seemingly spoiled for choice.But with Liverpool enjoying an embarrassment of riches, Newcastle is feeling Isak's absence keenly.
It wil be a concern for the rest of the league that Liverpool has strung together so many victories without Isak.
Howe has tried to be similarly gradual with Nick Woltemade, leaving him out from the start against Barcelona in midweek, but the scoring burden already sits squarely on the big German striker.
Anthony Gordon had been a regular makeshift striker in the league before his red card against Liverpool earned him a suspension.
Nick Woltemade of Newcastle United is substituted by Head Coach Eddie Howe.
Howe went on to express his hope that Newcastle may even be evolving into a better team in the absence of Isak.
As Howe and Newcastle get used to their new reality, it's another reminder to Liverpool that Slot has a world-class difference-maker on his books, just waiting to be unleashed