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Giovanni Leoni’s injury comes as a big blow to both the player and Liverpool, especially at such an early stage of the season.
Having been stretchered off on his debut against Southampton on Tuesday, it seems as though the 18-year-old will face a lengthy spell out now, with reports claiming he has torn the cruciate ligament in his left knee.
That creates a major issue for Arne Slot, with the Liverpool boss now reduced to just three recognized center-backs in his first-team squad, and with Premier League, Champions League and Carabao Cup commitments to deal with, his side could be stretched over the next few months.
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There is, of course, an opportunity for Slot and Richard Hughes to add to their squad, and potentially bring in a new defender to provide more cover in January, although that might require a change in approach from the club.
Liverpool.com has taken a look at its options in the New Year…
Plan A - Wait and see
Before Leoni's injury, it was being widely reported that Liverpool was not planning on making a January move for Marc Guehi, despite missing out on the Crystal Palace defender on deadline day.
Whether that stance will change now remains to be seen, but as things stand, it does seem as though the Reds will wait to get their man for free next summer.
Were any of those to pick up an injury, the Liverpool boss would have to fall back on his alternative options.
Andy Robertson, Milos Kerkez, Ryan Gravenberch and Wataru Endo would be the prime candidates to move into the center of defense should the worst happen, while the likes of Amara Nallo, Carter Pinnington and Wellity Lucky could be called up from the academy.
Plan B - Go early
Should Leoni's injury change Liverpool's stance, you would imagine that Guehi would be the first port of call
Liverpool could change its stance on a January move for Marc Guehi
Whatever happens between now and January though, Leoni's injury leaves the Reds with a big call to make ahead of the next transfer window.