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Klopp made six changes for the first leg against Atalanta last week, and it remains to be seen what decisions will be made for the reverse fixture in Italy this time around.
READ MORE: Liverpool handed quiet Europa League hope as Atalanta complaints made
READ MORE: Two players have to start against Atalanta - Liverpool have nothing left to lose
What that in mind, the ECHO has taken a look at three players who are arguably undroppable for Liverpool for the game at the Gewiss Stadium.
Return of Trent
The injury to Conor Bradley in the defeat to Crystal Palace will be a major blow to Liverpool during the run-in.
Given Liverpool will need a near-perfect game to have a chance of overcoming the deficit against Atalanta, Klopp may gamble and start Alexander-Arnold.
Gakpo conundrum
During Liverpool's injury crisis, Cody Gakpo was handed a continuous run of starts by Klopp while Diogo Jota, Mohamed Salah and Darwin Nunez were on the sidelines.
Could Klopp put his faith in the Netherlands international when it matters most this week?
Importance of Alexis
One player who has continued to highlight his importance to the Liverpool team is Alexis Mac Allister.
Even though recent results have not been what the Reds would have wanted, the midfielder has performed his role exactly as Klopp and the coaching staff would want.
Away at Atalanta, Liverpool will need a player comfortable in possession and can break down the opposition's defence.
However, Klopp will be mindful of not giving Mac Allister too much football to run the risk of the Argentina international suffering an injury when his importance to the team is so great.
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