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Slot's team made it all the way to Wembley last term, losing to Newcastle in the final, and their run began with a come-from-behind win at home to West Ham.The cup game is one of four Liverpool matches between now and the October international break, and each contains its own challenges.
Here are Mirror Football's latest lines from around Anfield as the Reds prepare to return to action.
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Bayern Munich have expressed internal regret over allowing Ryan Gravenberch to join Liverpool, it has been claimed.
And it's something former Liverpool manager Jurgen Klopp warned about before the summer tournament.
"They [Arsenal] were better and we were incredibly tired," Guardiola said after Sunday's draw at Arsenal.
"People don't realise, the [Champions League] game against Napoli was so emotional after that a recovery day then it's four or five hours to arrive in London, it's more fatigue and everything."
Speaking to Welt earlier in the summer, Klopp argued: "In the end, it's all about the game and not the surrounding aspects - and that's why the Club World Cup is the worst idea ever implemented in football in this regard." He said the number of summer competitions left players with little recovery time, suggesting we could see the effects sooner rather than later.
"This means no real recovery for the players who are there, neither physically nor mentally," he added.
Then after the game he congratulated me and told me that I should keep going like that.
"We are good.
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