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According to journalist Sacha Tavolieri, Liverpool have told Newcastle that if no agreement is reached by next week, they will move on to other targets.
Isak was not part of the Newcastle squad for the 0-0 draw with Aston Villa earlier on Saturday.
Meanwhile,The Mirror suggests that the Sweden international has earned himself a punishment through refusal to play, while talkSPORT add that even if the striker is not allowed to leave this summer, he will still refuse to play for the club again.
Elsewhere, club officials are said to still be working on a move for Marc Guehi of Crystal Palace.
Providing an update on his YouTube channel, Romano claimed that conversations are ongoing with Palace after reaching an agreement with the defender.
"On Liverpool, I insist they are still working for Marc Guehi," Romano said on YouTube.
But Marc Guehi wants to go to Liverpool.
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