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The first was when Sadio Mané scored a late winner in a 1-0 win in 2016 and the only other victory was the 4-1 during the 2021/22 season when Jordan Henderson, Mohamed Salah (twice) and Diogo Jota all netted.
But now Klopp needs another good showing and a clinical performance to keep pace at the top.
Mohamed Salah and Alexis Mac Allister were among those to be rested for the win over Fulham last Sunday but they are both highly likely to come back into the side.
Matt Addison - Cody Gakpo retains his place
Most of this team should pick itself, for me, though I would have been going with Diogo Jota again had he been fit.
I'm going to go with the height of Dominik Szoboszlai as well, though I wouldn't be against Wataru End? being in there.
Salah is a must in the attack after he was rested at the weekend while Cody Gakpo did enough to keep his place, especially with Jota now being out.
I'll go with Gakpo central and Luis Díaz off the left, with Darwin Núñez an impact substitute.
My starting XI: Alisson; Alexander-Arnold, Konaté, Van Dijk, Robertson; Szoboszlai, Mac Allister, Jones; Salah, Gakpo, Díaz
Predicted scoreline: 2-0 to Liverpool.
One thing to watch:Mohamed Salah to come back in, score, and prove a point.
Liam Prenderville - Darwin Núñez is recalled
Jürgen Klopp made changes at Fulham on Sunday and those who came in did well.
I think Wataru End? will keep his place in midfield, with Alexis Mac Allister and Dominik Szoboszlai returning in front of him.
Diogo Jota's injury means at least one change will be needed in the attack with Mohamed Salah replacing him.
That means Luis Díaz switching to the left and I think Darwin Núñez might just get the nod over Cody Gakpo, despite his recent good form.
My starting XI: Alisson; Alexander-Arnold, Konaté, Van Dijk, Robertson; End?, Szoboszlai, Mac Allister; Salah, Núñez, Díaz
Predicted scoreline: 3-1 to Liverpool.
One thing to watch: Luis Díaz to cause Ashley Young all sorts of problems.