Liverpool vs Southampton LIVE - Alexander Isak goal, score, commentary stream

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Isak has played around 100 minutes for club and country since May and having come off the bench for Saturday's 2-1 win over Everton in the Merseyside derby, the Sweden international leads the line against the Championship outfit this evening.

Giovanni Leoni is handed his Liverpool debut following his mid-August move from Parma, with the young Italian centre-back named alongside Joe Gomez, who makes a first start of the season.

Giorgi Mamardashvili, the £29m summer signing from Valencia, is given his debut in lieu of Alisson Becker, who was present at Monday night's Ballon d'Or ceremony in Paris alongside club captain Virgil van Dijk.

Federico Chiesa begins on the right side of the front three and Rio Ngumoha is given just his second start for the club after his 2024 switch from Chelsea.

Hugo Ekitike and Milos Kerkez are on the bench alongside Kaide Gordon, Rhys Williams and Jayden Danns.

Liverpool: Mamardashvili; Frimpong, Leoni, Gomez, Robertson; Endo, Jones; Chiesa, Nyoni, Ngumoha; Isak.

Subs: Woodman, Kerkez, Bradley, Ekitike, Williams, Gordon, Morrison, Pilling, Danns.