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Prior to this transfer shocker, Newcastle announced that Isak would be absent from its preseason tour of Asia due to a minor thigh injury.
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Should he depart St James' Park for another Premier League outfit, his alleged wage demands could make him one of the highest earners in the league's history.
While Liverpool's Premier League rival Manchester City has the financial muscle to chase the striker, BBC Sport suggests it is "unlikely" to do so.
Erling Haaland, one of the Premier League's top earners, is under contract until the summer of 2034.
As for the Reds, they are fans of the player, and they would be more than happy to sign him.
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Pep Guardiola isn't expected to swoop for Isak this summer.
Howe addressed the speculation surrounding his star forward, explaining why Isak didn't play against Celtic during a recent friendly.
"He travelled back to Glasgow with us, but I decided to send him home due to the speculation around him.
"Both (Joelinton and Isak) are fit but not ready to play.
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