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Cash sustained "a severe bruise" to his quadriceps whilst representing Poland during the international break, whereas Onana and Kamara are both nursing hamstring problems.Unai Emery faces a delicate balancing act with the trio, whilst Ross Barkley remains likely to be deemed lacking match sharpness.
Bournemouth
Cherries skipper Adam Smith picked up a hamstring problem prior to the international break.
Yunus Konak might make his comeback after an ankle problem.
Read more: Rio Ferdinand makes new Arsenal Premier League title prediction three games in
Bukayo Saka remains injured for Arsenal (Image: Getty)
Brighton
Mats Wieffer could feature for the Seagulls as they face Bournemouth, though Adam Webster and Solly March remain long-term casualties.
Burnley
Connor Roberts might make his comeback from a knee problem, though Jordan Beyer, Zeki Amdouni and Manuel Benson remain unavailable for Scott Parker's squad.
Chelsea
Doubt surrounds Cole Palmer's availability after he suffered a setback during the warm-up prior to Chelsea's 5-1 triumph at West Ham with a groin complaint.
Dario Essugo has had surgery on a thigh problem sustained while on international duty with Portugal's under-21s.
Maresca might rest Reece James on the bench after he played in both England matches during the international break; his playing time continues to be monitored at Chelsea.
Crystal Palace
Oliver Glasner managed to retain Marc Guehi on deadline day, but he does have injuries to contend with.
Jeremie Frimpong could make his comeback this weekend, having resumed training following a thigh problem picked up last month.
Manchester City
Pep Guardiola is grappling with the most extensive injury list of any Premier League manager following Omar Marmoush's knee problem sustained whilst on international duty with Egypt.
He will go away for tests and maybe see a specialist to see."
Fellow new signing Jacob Ramsey remains sidelined with an ankle problem sustained in the goalless stalemate with Leeds before the international break, whilst Anthony Gordon faces suspension following his red card for a reckless challenge on Virgil van Dijk.