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It was his first Anfield match since confirming he will leave his boyhood club at the end of the season, with a free transfer to Real Madrid anticipated.
Alexander-Arnold was not named in the starting XI to begin with, as head coach Arne Slot had alluded to beforehand.
In a crowd of 60,000, there's no doubt there will be a lot of unhappy people with the situation, that's understandable," he said.
"Away at Leicester there was a few boos there but I don't believe any player putting on that red shirt, trying to get three points or win a trophy should be booed.
"I understand there's a lot of ill-feeling, I get that, some people outside of Liverpool can't grasp that, I do but booing one of your own players is not for me."
In light of the situation as Alexander-Arnold prepares to leave the club, ECHO writers have their say over whether the reaction of Liverpool supporters was justified.
Richard Garnett
Having rocked up at Anfield every other week for over 30 years, I can count on one hand the number of times I've heard a Liverpool player or ex-player booed.
Yes.
Everything that he has said in the past about hoping for a glorious future captaining his boyhood club has amounted to nothing in what has been a drawn-out contract saga.
Steven Gerrard would have killed to not only win the trophies Alexander-Arnold has won with Liverpool in his career so far, but be in the position this club finds themselves in now.
Trent is only leaving to pursue a new challenge, after all.
Yes, leaving on a free transfer is not ideal, but make no mistake: deciding to leave your boyhood club is a tough and emotional decision.
Booing a player who is still at the Reds, still pulling on the shirt and representing his boyhood club, is a step too far, I feel.
Jake Stokes
I understand why Liverpool supporters booed Alexander-Arnold.
While Alexander-Arnold orchestrated a free transfer behind the scenes, supporters believed he was remaining on course to become the club's next captain.
At the end of the day, leaving your boyhood club on a free transfer is a big call